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ADMEWORKS DDI Simulator - Drug-drug interactions


ADMEWORKS DDI Simulator is cutting-edge Fujitsu’s software product addressed towards pharmaceutical sector. DDI Simulator is a software application for assessing the risk of potential drug-drug interactions, allowing the user to perform both quantitative simulations of Competitive and Mechanism-based inhibitions. The system was developed based on the results of the Human Animal Bridging (HAB) project, a nonprofit research organization in Japan, under the supervision of Dr. Kazuya Maeda of the University of Tokyo.

Advantages of using DDI Simulator

  • More accurate predictions than simple approximation method.

  • Allows prediction using in-house compound as inhibitor or substrate.

  • Evaluate risk based on AUC ratio, Cmax ratio or changes in elimination half-life.